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Abstract #0029

Free-breathing liver fat quantification with combined multi-echo Dixon and 3D radial stack-of-stars in children and adults at 3T and 1.5T

Shuo ZHANG1,2, Teresa Nolte2, Masami Yoneyama3, Sven Nebelung2, Christiane Kuhl2, Alexandra Barabasch2, and Jochen Herrmann4
1Philips GmbH Market DACH, Hamburg, Germany, 2Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, Aachen, Germany, 3Philips Japan, Tokyo, Japan, 4Department of Diagnostic and Interventional Radiology and Nuclear Medicine, Section of Pediatric Radiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Synopsis

Multi-echo gradient-echo Dixon based on the chemical shift method is currently the standard for non-invasive in vivo quantification of the liver fat but requires breath-holding. In young children or sick patients this is often challenging or not feasible. Despite recent attempts using different free-breathing approaches to mitigate patient motions, these are not widely available or routinely used. In this work we employ the multi-echo Dixon sequence with 3D pseudo-golden angle radial stack-of-stars readout for free-breathing liver fat assessment and report our initial results in children and adults at 3T and 1.5T with phantom validation and comparison to the standard method.

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Keywords