Abstract #0042

High-fidelity submillimeter-isotropic-resolution diffusion MRI through gSlider-BUDA and circular EPI with S-LORAKS reconstruction

Congyu Liao^1,2, Uten Yarach³, Xiaozhi Cao^1,2, Siddharth Srinivasan Iyer⁴, Nan Wang^1,2, Tae Hyung Kim^5,6, Berkin Bilgic^5,6, Adam Kerr^1,7, and Kawin Setsompop^1,2

¹Department of Radiology, Stanford University, Stanford, CA, United States, ²Department of Electrical Engineering, Stanford University, Stanford, CA, United States, ³Radiologic Technology Department, Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand, ⁴Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁵Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ⁶Department of Radiology, Harvard Medical School, Boston, MA, United States, ⁷Stanford Center for Cognitive and Neurobiological Imaging, Stanford University, Stanford, CA, United States

Synopsis

BUDA-cEPI combines a circular-EPI (cEPI) trajectory with Blip-Up and Down Acquisition (BUDA), to achieve high-fidelity diffusion imaging. It employs full-ramp-sampling to efficiently cover a circular k-space to shorten the readout-train and mitigate T₂*-blurring. For further readout-shortening, a combined phase-encoding(PE) & readout(RO) partial-Fourier (pF) is employed, where PE-pF is resolved via opposing the blip-up and down EPI-shots, and S-LORAKS reconstruction is used to effectively fill-out the remaining k-space. This resulted in an acquisition with markedly-reduced TE and ~40% reduced echo-train-length and T₂*-blurring compared to standard-EPI at the same R_inplane and PE-pF. To achieve high-SNR, BUDA-cEPI is also combined with a gSlider-multi-slab acquisition.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.