Abstract #0053

Toward a 1-minute high-resolution brain exam - MR Fingerprinting with fast reconstruction and ML-synthesized contrasts

Sophie Schauman¹, Siddharth Srinivasan Iyer^1,2, Mahmut Yurt¹, Xiaozhi Cao¹, Congyu Liao¹, Zheng Zhong¹, Guanhua Wang³, Greg Zaharchuk¹, Shreyas Vasanawala¹, and Kawin Setsompop¹

¹Department of Radiology, Stanford University, Stanford, CA, United States, ²Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ³Deptartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States

Synopsis

MRI is a notoriously slow imaging method, but in recent years many technical developments have improved acquisition speed. However, many of these new fast sequences have not made their way to clinical practice. Barriers to uptake include long reconstruction times, diminished image quality, and non-standard contrast in the resulting images. Our objective is to translate a ~1 minute MRF sequence into clinical practice, providing five high quality images with common clinical contrasts at 1 mm isotropic-resolution, as well as quantitative T1, T2, and proton density maps, all within a 5 minute reconstruction pipeline that we have deployed clinically.

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