As part of the Multichannel Illinois Institute of Technology & Rush university Aging (MIITRA) atlas project, the present work (A) developed high quality 0.5mm isotropic resolution T1-weighted (T1w) and diffusion tensor imaging (DTI) templates in common space using data from a large, diverse, community cohort of non-demented older adults, and (B) compared the new templates to existing templates of the older and younger adult brain. The new templates exhibited higher image quality, were more representative of the older adult brain, and allowed higher spatial normalization accuracy across subjects and across modalities compared to other templates.
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