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Abstract #0069

MIITRA atlas: T1w and DTI templates of the older adult brain in a common space with 0.5mm resolution

Yingjuan Wu1, Abdur Raquib Ridwan1, Mohammad Rakeen Niaz1, David A. Bennett2, and Konstantinos Arfanakis1,2
1Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, United States, 2Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, United States


As part of the Multichannel Illinois Institute of Technology & Rush university Aging (MIITRA) atlas project, the present work (A) developed high quality 0.5mm isotropic resolution T1-weighted (T1w) and diffusion tensor imaging (DTI) templates in common space using data from a large, diverse, community cohort of non-demented older adults, and (B) compared the new templates to existing templates of the older and younger adult brain. The new templates exhibited higher image quality, were more representative of the older adult brain, and allowed higher spatial normalization accuracy across subjects and across modalities compared to other templates.

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