Perfusion territory shifts in asymptomatic carotid artery stenosis measured by super-selective arterial spin labelling
Gabriel Hoffmann1,2, Miriam Reichert1, Jens Göttler1, Michael Helle3, Kim van de Ven4, Claus Zimmer1,2, Moritz Hernandez Petzsche1,2, Hans Liebl1,5, Nico Sollmann1,6, Christine Preibisch1,2, and Stephan Kaczmarz1,2,7
1Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany, 2TUM-Neuroimaging Center, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany, 3Philips Research, Hamburg, Germany, 4Philips Healthcare, Best, Netherlands, 5Department of Radiology, Neuroradiology and Minimal-Invasive Therapy, Klinikum Bogenhausen, Munich, Germany, 6Department of Diagnostic and Interventional Radiology, University Hospital Ulm, Ulm, Germany, 7Philips Healthcare, Hamburg, Germany
Vessel-selective imaging is promising to examine collateral blood supply in asymptomatic internal carotid artery stenosis (ICAS). Established modalities like digital subtraction angiography are invasive, not quantitative and associated with potential complication risks. A viable non-invasive alternative is super-selective arterial spin labelling, providing perfusion territories of individual arteries. We present data from seven asymptomatic ICAS patients and four age-matched healthy controls. We compared individual perfusion territory maps to an atlas of vascular territories and evaluated intra-hemispheric differences, allowing for quantitative assessment of stenotic mal-perfusion as well as compensatory collateral blood supply from the contralateral ICA.
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