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Abstract #0087

Evidence for Improved Left Atrial Blood Flow Dynamics after Pulmonary Vein Isolation in Patients with Atrial Fibrillation

Maurice Pradella1,2, Justin J Baraboo1, Suvai Gunasekaran1, Mitchell A Collins1, Anthony Maroun1, Amanda L DiCarlo1, Rishi Arora3, Phil Greenland4, Rod Passman3, and Michael Markl1
1Department of Radiology, Northwestern University, Chicago, IL, United States, 2Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland, 3Department of Cardiology, Northwestern University, Chicago, IL, United States, 4Department of Preventive Medicine, Northwestern University, Chicago, IL, United States


Atrial fibrillation (AF) significantly increases stroke risk which is attributed to thrombus formation in the left atrium (LA) and to a greater extent the LA appendage (LAA). In this study, we investigated 4D-flow MRI-derived blood flow metrics from pre- and post-ablation exams in 26 AF patients undergoing pulmonary vein isolation (PVI). Blood stasis in both the LA and LAA significantly decreased in the post-PVI 4D-flow MRI. Furthermore, LA and LAA volumes also significantly decreased. Our results suggest that 4D-flow MRI was sensitive to detect treatment-related changes of LA and LAA flow metrics implicated on thromboembolic risk in AF patients.

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