Abstract #0099

The role of facet joint arthropathy in chronic low back pain and its association with adjacent paraspinal muscle composition

Nico Sollmann^1,2,3, Noah B. Bonnheim⁴, Gabby B. Joseph¹, Ann A. Lazar⁵, Ravi Chachad¹, Jiamin Zhou¹, Jeannie F. Bailey⁴, Xiaojie Guo⁴, Thomas M. Link¹, Aaron J. Fields⁴, and Roland Krug¹

¹Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, ²Department of Diagnostic and Interventional Radiology, University Hospital Ulm, Ulm, Germany, ³Department of Diagnostic and Interventional Neuroradiology, Technical University of Munich, Munich, Germany, ⁴Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, United States, ⁵Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States

Synopsis

Low back pain (LBP) is a global health burden, but patient phenotyping based on imaging that would facilitate timely and effective treatment regimens lacks behind. One issue is that associations between different structures at the degenerative lumbar spine are not yet well characterized. In this study we revealed that facet joint arthropathy (FJA) at level L4/L5 is associated with the fat fraction (FF) of adjacent paraspinal musculature (PSM) as derived from chemical shift encoding-based water-fat MRI (CSE-MRI), as well as with Modic-type endplate changes, endplate defects, and intervertebral degenerative disk disease (DDD) in patients with chronic LBP.

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