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Abstract #0125

Acquisition and data processing considerations in functional metabolic imaging using CEST

Solène Bardin1,2, Fawzi Boumezbeur1,2, and Luisa Ciobanu1,2
1NeuroSpin, CEA, Gif-sur-Yvette, France, 2Paris-Saclay University, Gif-sur-Yvette, France


Accelerated acquisitions with a CEST-linescan sequence coupled with the estimation of the local baseline for the analysis of the Z-spectra allow to simultaneously monitor dynamic changes at several CEST contributions induced by a controlled pH decrease. This approach can be a promising strategy for detecting functional induced metabolic changes devoid of confounding BOLD effects.

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