GraspCEST: Fast Free-Breathing 3D Steady-State CEST MRI Using Golden-Angle Radial Sparse MRI
Xiang Xu1, Ding Xia1, Kai Tobias Block2, and Li Feng1
1Department of Radiology and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R) and Department of Radiology, New York University School of Medicine, New York, NY, United States
In this project, we proposed a fast 3D CEST MRI technique called GraspCEST, which is based on the combination of CEST-prepared stack-of-stars golden-angle radial sequence and multicoil compressed sensing reconstruction. Using this technique, we were able to perform lipid suppressed, free-breathing 3D CEST imaging of the liver. We have demonstrated that it is possible to accelerate imaging speed and achieve full Z-spectra acquisition of the liver within 5 min. The GraspCEST technique can be a useful tool in studying glycoNOE in the liver.
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