Magnetic resonance elastography (MRE) allows for non-invasive determination of pancreatic visco-elastic properties in four consecutive breath-holds. The aim of this study was to develop and test a single breath-hold MRE acquisition accelerated using prospective undersampling and compressed sensing (CS) reconstruction. Testing was done on a retrospective undersampled phantom dataset and in-vivo. These showed that CS accelerated (R< 8.7), single breath-hold MRE is feasible without hampering visco-elastic reconstruction in tissues with low shear stiffness (|G*|<1.6kPa). Further research is necessary to guarantee accuracy of the measured shear stiffness, notably for high stiffness tissues such as tumors, and at higher acceleration factors.
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