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Abstract #0123

Feasibility of compressed sensing accelerated Ristretto magnetic resonance elastography in the pancreas

Anne-Sophie van Schelt1, Nienke P.M. Wassenaar1, Jurgen H. Runge1, Jules L. Nelissen1, Marian Troelstra1,2, Christian Guenthner3, Ralph Sinkus2,4, Jaap Stoker1, Aart J. Nederveen1, and Eric M. Schrauben1
1Radiology and Nuclear Medicine, Amsterdam UMC location AMC, Amsterdam, Netherlands, 2Department of Imaging Sciences and Biomedical Engineering, King’s College London, London, United Kingdom, 3Department of Biomed, ETH Zurich, Zurich, Switzerland, 4Inserm U1148, LVTS, Univeristy Paris Diderot, Paris, France


Magnetic resonance elastography (MRE) allows for non-invasive determination of pancreatic visco-elastic properties in four consecutive breath-holds. The aim of this study was to develop and test a single breath-hold MRE acquisition accelerated using prospective undersampling and compressed sensing (CS) reconstruction. Testing was done on a retrospective undersampled phantom dataset and in-vivo. These showed that CS accelerated (R< 8.7), single breath-hold MRE is feasible without hampering visco-elastic reconstruction in tissues with low shear stiffness (|G*|<1.6kPa). Further research is necessary to guarantee accuracy of the measured shear stiffness, notably for high stiffness tissues such as tumors, and at higher acceleration factors.

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