Abstract #0152

Field-Cycling imaging identifies breast cancer at low magnetic field strengths

Vasiliki Mallikourti¹, James Ross¹, Oliver Maier², Gareth Davies¹, Gerald Lip³, Markus Bödenler⁴, Rudolf Stollberger⁵, Yazan Masannat³, and Lionel Broche¹

¹Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, ²Institute of Medical Engineering, Graz University of Technology, Graz, Austria, ³Breast unit, Aberdeen Royal Infirmary, Aberdeen, United Kingdom, ⁴Institute of eHealth, University of Applied Sciences FH JOANNEUM, Graz, Austria, ⁵BioTechMed-Graz, Graz, Austria

Synopsis

Field-Cycling imaging (FCI) can image over a range of low magnetic field strengths (0.2 T to 0.2 mT) through rapid switching between magnetic field levels. This allows measuring the field-depended changes of the longitudinal T1 relaxation time, known as T1 dispersion, exploring new approaches for breast tumour contrast. FCI images were acquired from patients with breast tumours to generate multi field-T1 maps and T1 dispersions. The T1 maps exhibited visible contrast of the tumour region. T1 dispersion profiles from tumours differed from those in healthy breast tissues, showing that FCI can detect breast tumours at low field strengths.

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