The impact of the fat fraction in fat-water mixtures on the fat and water T1s is an open question, with variable observations reported in phantoms, in vivo in bone marrow, and in liver. This work investigated variations of fat and water T1 as a function of fat content in phantoms in the presence of a water relaxation enhancing agent (MnCl2). Fat fraction and MnCl2 impacted both the water and fat T1s, in different ways. Our observations may shed light on variable trends of fat and water T1 as a function of fat content reported in the literature.
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