First in vivo Myocardial Perfusion Measurements using Intra-arterial Spin Labeling during MR-guided Coronary Interventions in Pigs
Simon Reiss1, Kevin Waescher1, Thomas Lottner1, Ali Caglar Özen1,2, Timo Heidt3, Constantin von zur Mühlen3, and Michael Bock1
1Dept. of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 2German Consortium for Translational Cancer Research Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany, 3Dept. of Cardiology and Angiology I, University Hospital Freiburg and Faculty of Medicine, University of Freiburg, Freiburg, Germany
Arterial spin labeling (ASL) provides a method for myocardial perfusion quantification without exogenous contrast agents. In MR-guided coronary catheterizations, perfusion measurements can provide a valuable tool to diagnose myocardial perfusion deficits and monitor the success of the intervention. In these interventions, catheters are usually visualized by active receive RF coils attached to the catheter. Using these active coils in transmit mode would enable intra-arterial spin labeling (iASL) in the coronary arteries with an increased labeling efficiency compared to conventional ASL. Here, we show the first in vivo results using iASL for myocardial perfusion measurements during coronary interventions in pigs.
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