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Abstract #0216

RR-Resolved 5D flow for Decoding the Impact of Cardiac Rhythm on Left Atrial Flow Dynamics in Atrial Fibrillation and Stroke

Justin Baraboo1, Elizabeth Weiss1, Maurice Pradella1, Liliana Ma1, Julia Hwang1, Suvai Gunasekaran1, Mariana Falcão2, Christopher W Roy2, Matthias Stuber2, Rod Passman1, Daniel Kim1, and Michael Markl1
1Northwestern University, Chicago, IL, United States, 2University of Lausanne, Lausanne, Switzerland

Synopsis

RR-resolved 5D flow is a novel MRI technique that can acquire time-resolved 3D hemodynamics for varying RR-interval durations during atrial fibrillation (AF) (5D = 3D+cardiac time+RR-interval duration). The purpose of this study was to apply RR-resolved 5D flow MRI in a cohort of AF patients with and without a prior history of stroke. We saw significantly lowered left atrial peak velocities and trends toward higher atrial blood stasis in AF patients with previous stroke history vs no previous stroke history who underwent arrhythmia during MRI acquisition. RR-resolved 5D flow may be a promising approach for cardiovascular imaging in arrhythmic patients.

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Keywords