Abstract #0221
Mapping of Metabolite Profile of Urine of Patients with Chronic Prostatitis, Prostate Cancer and Healthy Controls: A Pilot NMR Metabolomic Study
Naranamangalam R Jagannathan1,2,3, R Ravikanth Reddy1, Arun Kumar Shirshetty4, Samsudeen Marwan5, Deepak Masanam4, and Ananathakrishanan Sivaraman5
1Dept. of Radiology, Chettinad Hospital & Research Institute, Kelambakkam, India, 2Dept. of Electrical Engineering, Indian Institute of Technology, Chennai, India, 3Radiology, Sri Ramachandra Inst. of Higher Education and Research, Chennai, India, 4Dept. of Urology, Chettinad Hospital & Research Institute, Kelambakkam, India, 5Chennai Urology and Robotics Institute Hospital, Chennai, India
Synopsis
The present study aims to evaluate a comprehensive metabolic profiling of patients with chronic prostatitis (PT) by investigating their urine samples and compare it with the prostate cancer (PCa) patients and healthy controls (HC) using 1H nuclear magnetic resonance (NMR) metabolomics. The metabolic profile of chronic prostatitis patients falls between that seen for PCa and HC. This pilot study showed that NMR metabolomics may be useful to differentiate patients with PT from PCa and HC.
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