Quantitative time of flight (qTOF) is a recently described 3D magnetic resonance angiography (MRA) technique for simultaneous luminal and hemodynamic evaluation of the intracranial arteries, that provides higher contrast-to-noise ratio efficiency than 3D phase contrast (PC) MRA and reduces in-plane flow displacement artifacts visible on standard 3D TOF MRA. We hypothesized that the use of a quiescent interval slice-selective-based data acquisition strategy (qQISS) that boosts arterial-to-background contrast might improve the quantitation of intracranial arterial flow velocity. Compared to qTOF MRA, we found that qQISS MRA improved agreement with PC MRA for measuring intracranial blood velocity.
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