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Abstract #0223

300 mT/m diffusion MRI 'below the neck': First results in healthy prostate

Malwina Molendowska1, Marco Palombo1, Fabrizio Fasano2,3, Derek K. Jones1, Daniel C. Alexander4, Eleftheria Panagiotaki4, and Chantal Tax1,5
1Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom, 2Siemens Healthcare Ltd, Camberly, United Kingdom, Camberly, United Kingdom, 3Siemens Healthcare GmbH, Erlangen, Germany, Erlangen, Germany, 4Centre for Medical Image Computing, University College London, London, United Kingdom, 5Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands


This work showcases the first ever use of ultra-strong gradient in ’below the neck’ human MRI. It assesses the benefits, compared to more commonly-available gradient strengths, of 300mT/m gradients for comprehensive characterization of the prostate gland. Leveraging such gradient amplitudes enables unique tissue contrasts, with a potential to improve specificity and/or sensitivity of current MRI methods for prostate cancer characterisation and detection.

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