Abstract #0223

300 mT/m diffusion MRI 'below the neck': First results in healthy prostate

Malwina Molendowska¹, Marco Palombo¹, Fabrizio Fasano^2,3, Derek K. Jones¹, Daniel C. Alexander⁴, Eleftheria Panagiotaki⁴, and Chantal Tax^1,5

¹Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom, ²Siemens Healthcare Ltd, Camberly, United Kingdom, Camberly, United Kingdom, ³Siemens Healthcare GmbH, Erlangen, Germany, Erlangen, Germany, ⁴Centre for Medical Image Computing, University College London, London, United Kingdom, ⁵Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands

Synopsis

This work showcases the first ever use of ultra-strong gradient in ’below the neck’ human MRI. It assesses the benefits, compared to more commonly-available gradient strengths, of 300mT/m gradients for comprehensive characterization of the prostate gland. Leveraging such gradient amplitudes enables unique tissue contrasts, with a potential to improve specificity and/or sensitivity of current MRI methods for prostate cancer characterisation and detection.

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