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Abstract #0225

Transrectal magnetic resonance imaging and robot- guided focal laser ablation of prostate cancer: preliminary results of a phase 2 study.

Annemarijke Van Luijtelaar1, J.P. Michiel Sedelaar2, Joyce G.R. Bomers1, and Jurgen J. Fütterer1
1Medical Imaging, Radboudumc Nijmegen, Nijmegen, Netherlands, 2Urology, Radboudumc Nijmegen, Nijmegen, Netherlands


Magnetic resonance imaging-guided focal laser ablation is used as alternative to radical treatment while preserving healthy tissue and subsequently reduce treatment-related morbidity in patients with localized prostate cancer. Preliminary results of this prospective, non-randomized, clinical phase 2 study using a remote-controlled manipulator, show promising results in both oncological and functional outcomes in a group of 20 patients with low- to intermediate-risk (Gleason Score ≤ 4+3) prostate cancer. Transrectal magnetic resonance imaging-guided focal laser ablation is a promising outpatient procedure under local anesthesia for localized prostate cancer. It provides a fast and minimally-invasive strategy while reducing treatment related complications and side-effects.

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