Whole brain ex vivo diffusion MRI needs high b-value encoding to compensate for the reduced diffusivity, requiring human brain scanners with ultra-strong diffusion gradients. At that regime, eddy currents become too severe, to the point image distortions and ghosting artifacts cannot be enough mitigated with conventional image reconstruction and post-processing approaches. On a 3T Connectom scanner , we demonstrate the importance of spatiotemporal field monitoring to measure and model eddy currents. When Fourier reconstruction is informed with the unwanted spatiotemporal evolution of the phase, distortion- and ghosting-free high-resolution DW images can be achieved.
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