Abstract #0258
Evaluation of Single-shot EPI with Sub-millimeter Resolution fMRI on the Next-Generation 7T brain scanner.
Alexander JS Beckett1,2, An T Vu3,4, Sinyeob Ahn5, Salvatore Torrisi1,2, Jonathan R Polimeni6,7, Essa Yacoub8, Kawin Setsampop9,10, Berkin Bilgic6,7, Shajan Gunamony11,12, Andreas Potthast13, Peter Dietz13, Yulin Chang5, and David A Feinberg1,2
1University of California, Berkeley, CA, United States, 2Advanced MRI Technologies, Sebastopol, CA, United States, 3Radiology, University of California, San Francisco, CA, United States, 4San Francisco Veteran Affairs Health Care System, San Francisco, CA, United States, 5Siemens Medical Solutions, Malvern, PA, United States, 6Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 7Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, 8Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 9Department of Radiology, Stanford University, Stanford, CA, United States, 10Department of Electrical Engineering, Stanford University, Stanford, CA, United States, 11Imaging Centre of Excellence, University of Glasgow, Glasgow, United Kingdom, 12MR CoilTech Limited, Glasgow, United Kingdom, 13Siemens Healthcare GmbH, Erlangen, Germany
Synopsis
The newly developed “Impulse” head gradient (200 mT/m Gmax, 900 T/m/s) on the NexGen 7T scanner has been specifically designed to allow for high-resolution single-shot EPI with minimal distortions and blurring by minimizing echo spacing. In conjunction with the increased SNR and reduced g-factor noise afforded by the 96 channel receive array coil, mesoscale fMRI at 0.45mm and 0.6mm isotropic resolutions can be robustly achieved in human subjects.
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