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Abstract #0259

Spin-echo line-scanning at 7T

Luisa Raimondo1, Tomas Knapen1,2, Serge O Dumoulin1,2, Wietske van der Zwaag1, and Jeroen C.W Siero1,3
1Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, 2VU University, Amsterdam, Netherlands, 3Radiology, University Medical Centre, Utrecht, Netherlands


We implemented spin-echo line-scanning (SELINE) fMRI through a simple rotation of the spin-echo refocusing gradient to a plane perpendicular to the excited slice and removing the phase encode gradient. This technique promises a combination of high spatio-temporal resolution and specificity of functional responses to the microvasculature. We compared SELINE data to the corresponding gradient-echo version (GELINE). We demonstrate that SELINE showed much improved line selection compared to GELINE, albeit at the cost of a significant drop in functional sensitivity. The low functional sensitivity needs to be addressed before SELINE can be applied.

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