Meeting Banner
Abstract #0269

Autonomic Function Regulates the Default-Mode Network in Rats

Jiayue Cao1, Xiaokai Wang1, and Zhongming Liu1,2
1Biomedical Engineering, University of Michigan, ANN ARBOR, MI, United States, 2Electrical engineering and computer science, University of Michigan, ANN ARBOR, MI, United States


The default mode network (DMN) is central to cognition. Consistent across species, functional connectivity (FC) of DMN exhibits partly similar patterns across brain states, including wakefulness, sleep, sedated or anesthetized states. Regions in DMN are also involved in regulating visceral organs. It is likely that DMN facilitates visceral physiology to maintain homeostasis in states of unconsciousness. However, the evidence for the association between autonomic function and DMN is sparse and piecemeal. Here, we use fMRI in rat models to investigate how vagal nerve de-innervation and stimulation affect the DMN and its interaction with other regions related to autonomic function.

This abstract and the presentation materials are available to members only; a login is required.

Join Here