The worldwide increase in sugar consumption is a major health concern. The contribution of fructose to the epidemic of metabolic disorders is controversial. This study investigated differences between glucose and fructose metabolism in the liver using dynamic deuterium metabolic imaging (DMI). Deuterium signal time curves after bolus injection and slow infusion were successfully acquired and showed different patterns. It was found that the peak concentration and conversion of deuterated glucose was different from that of fructose, indicating faster turnover of the latter. Overall, these methods could potentially lead to better understanding of healthy liver metabolism and aberrations in metabolic diseases.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords