CMR plaque imaging has the potential to predict future coronary events, but is limited by low spatial-resolution, misregistration artefacts, respiratory motion related image quality degradation and unpredictable acquisition times. Here we clinically evaluate the feasibility of a novel 3D free-breathing, non-rigid motion corrected, non-contrast CMR sequence (iT2prep-BOOST) that enables simultaneous, high-resolution visualisation of the coronary arteries and high-risk plaque features on co-registered bright and black blood images in patients presenting with acute myocardial infarction. We found that iT2prep-BOOST can simultaneously visualise coronary artery stenosis as well as culprit and bystander coronary plaque, as validated against invasive coronary angiography and OCT.
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