Abstract #0330

Feasibility of simultaneous non-contrast coronary MR angiography and vulnerable plaque imaging in acute myocardial infarction

Reza Hajhosseiny^1,2, Adam Hartley², Graham Cole², Camila Munoz¹, Amarjit Sethi², Rasha Al-Lamee², Deepa Gopalan², Ben Ariff², Raffi Kaprielian², Karl Kunze^3,4, Radhouene Neji^3,4, Claudia Prieto¹, Ramzi Khamis², and René M Botnar¹

¹Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ²National Heart and Lung Institute, Imperial College London, London, United Kingdom, ³MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, ⁴School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Synopsis

CMR plaque imaging has the potential to predict future coronary events, but is limited by low spatial-resolution, misregistration artefacts, respiratory motion related image quality degradation and unpredictable acquisition times. Here we clinically evaluate the feasibility of a novel 3D free-breathing, non-rigid motion corrected, non-contrast CMR sequence (iT2prep-BOOST) that enables simultaneous, high-resolution visualisation of the coronary arteries and high-risk plaque features on co-registered bright and black blood images in patients presenting with acute myocardial infarction. We found that iT2prep-BOOST can simultaneously visualise coronary artery stenosis as well as culprit and bystander coronary plaque, as validated against invasive coronary angiography and OCT.

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