Non-contrast-enhanced free-breathing thoracic MRA using gated REACT at 3T in small children with congenital heart disease
Alexander Isaak1, Narine Mesropyan1, Christopher Hart2, Dmitrij Kravchenko1, Christoph Endler1, Leon M. Bischoff1, Shuo Zhang3, Christoph Katemann3, Oliver Weber3, Daniel Kuetting1, Ulrike Attenberger1, Darius Dabir1, and Julian A. Luetkens1
1Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany, 2Department of Diagnostic and Interventional Radiology & Department of Pediatric Cardiology, University Hospital Bonn, Bonn, Germany, 3Philips GmbH Market DACH, Hamburg, Germany
Application of high-resolution 3D MR angiography (MRA) in small children with congenital heart disease (CHD) is challenging and generally requires contrast agent administration. In a cohort of pediatric CHD patients (median age: 4 years), non-contrast-enhanced free-breathing gated 3D mDixon REACT-MRA provided comparable overall image quality to contrast-enhanced free-breathing 3D mDixon steady-state MRA for assessment of the thoracic vasculature. REACT-MRA allowed for accurate and reliable vessel size measurements. Although fat-water separation artifacts were observed, they could be extenuated by reconstruction of in- and out-of-phase images. Gated REACT-MRA allows for a contrast-free assessment of the thoracic vasculature in small children with CHD.
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