Abstract #0328

Gadolinium-free Bright and Black-Blood 3D whole-heart MRI for efficient anatomical assessment in patients with Congenital Heart Disease

Anastasia Fotaki¹, Kuberan Pushparajah¹, Reza Hajhosseiny¹, Alina Schneider¹, Karl Kunze^1,2, Radhouene Neji^1,3, Harith Alam⁴, Alessandra Frigiola⁴, René Botnar^1,5, and Claudia Prieto^1,5

¹Biomedical Engineering, King's College London, London, United Kingdom, ²MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, ³MR Research Collaborations, Siemens Healthcare Limited, London, United Kingdom, ⁴Guy’s and St Thomas’s Hospital, London, United Kingdom, ⁵Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

A recently developed sequence, the Magnetisation Transfer Contrast Bright Blood phase SensiTive (MTC-BOOST), enables free-breathing simultaneous acquisition of a bright-blood and black-blood 3D whole-heart dataset. We sought to compare the acquisition time, image quality and diagnostic performance of the proposed MTC-BOOST against the native clinical T2-prep bSSFP and the contrast-enhanced (CE) T2-prep bSSFP sequence in a cohort of patients with Congenital Heart Disease. Our study showed that MTC-BOOST offers good delineation of the intracardiac and vascular anatomy that is comparable to the clinical CE T2prep bSSFP and superior to the non-CE T2-prep bSSFP while offering a shorter acquisition time.

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