Gadolinium-free Bright and Black-Blood 3D whole-heart MRI for efficient anatomical assessment in patients with Congenital Heart Disease
Anastasia Fotaki1, Kuberan Pushparajah1, Reza Hajhosseiny1, Alina Schneider1, Karl Kunze1,2, Radhouene Neji1,3, Harith Alam4, Alessandra Frigiola4, René Botnar1,5, and Claudia Prieto1,5
1Biomedical Engineering, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, 3MR Research Collaborations, Siemens Healthcare Limited, London, United Kingdom, 4Guy’s and St Thomas’s Hospital, London, United Kingdom, 5Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile
A recently developed sequence, the Magnetisation Transfer Contrast Bright Blood phase SensiTive (MTC-BOOST), enables free-breathing simultaneous acquisition of a bright-blood and black-blood 3D whole-heart dataset. We sought to compare the acquisition time, image quality and diagnostic performance of the proposed MTC-BOOST against the native clinical T2-prep bSSFP and the contrast-enhanced (CE) T2-prep bSSFP sequence in a cohort of patients with Congenital Heart Disease. Our study showed that MTC-BOOST offers good delineation of the intracardiac and vascular anatomy that is comparable to the clinical CE T2prep bSSFP and superior to the non-CE T2-prep bSSFP while offering a shorter acquisition time.
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