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Abstract #0341

Combined Angiographic, Structural and Perfusion Radial Imaging using Arterial Spin Labeling

Thomas W Okell1, Joseph G Woods2, and Mark Chiew1
1Wellcome Centre for Integrative Neuroimaging (FMRIB), Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 2CFMRI, Department of Radiology, University of California San Diego, San Diego, CA, United States

Synopsis

A Combined Angiographic, Structural and Perfusion Radial Imaging using Arterial Spin Labeling (CASPRIA) pulse sequence is presented which allows the simultaneous acquisition of non-contrast dynamic angiograms, quantitative perfusion maps and multi-contrast T1-weighted structural images within a single six-minute scan. Compared to conventional imaging methods, which took 70% longer to acquire, CASPRIA yielded comparable quantitative perfusion estimates, dynamic (rather than static) angiography with improved distal vessel visibility and structural images with greater contrast flexibility. With further work, the estimation of quantitative tissue T1 values could also be possible.

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Keywords