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Abstract #0349

Cartilage T2 Relaxation Times are Related to Walking Asymmetries in Osteoarthritic Knees

Amelia Kruse1, Austin Carcia1, Adam Bradshaw1, Charles Ho1, Johnny Huard1, Scott Tashman1, and Lauren Watkins1
1Steadman Philippon Research Institute, Vail, CO, United States


In this exploratory study, we examine relationships between joint function and cartilage composition in individuals with knee osteoarthritis (OA). MRI T2 relaxation times were used to assess articular cartilage and joint kinematics were recorded over walking gait cycles using video-motion analysis. There were significant correlations between cartilage T2 relaxation times and knee flexion, extension, and swing-stance ratio in both affected and contralateral legs. MRI measures of cartilage quality and joint function provide complimentary information that may be useful in measuring disease progression and intervention effectiveness using MRI.

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