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Abstract #0348

High Frame Rate Strain and Viscoelastic Analysis on Bovine Tibiofemoral Joints During Compression

Woowon Lee1, Emily Y Miller2, Callan M Luetkemeyer1, and Corey P Neu1,2
1Paul M. Rady Department of Mechanical Engineering, University of Colorado, Boulder, CO, United States, 2Biomedical Engineering Program, University of Colorado, Boulder, CO, United States


Osteoarthritis (OA) is a degenerative process in cartilage mainly occurring in knee. OA affects the structure and function of cartilage thus, measuring the mechanical properties of cartilage is crucial. We use spiral DENSE MRI to quantify the mechanics of intact and defected bovine articular cartilage. The samples underwent cyclic compressive load and 27 frames are captured while the joint was compressed. Displacement and strain gradually increased over time and the defected cartilage showed higher strain in the tibiofemoral contact areas. We also found creep response in the defected cartilage which may be a potential biomarker for OA detection.

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