Abstract #0362

Shuttered Echo Planar fMRI with Dynamic Motion and Phase Correction

Saikat Sengupta^1,2, Jonathan R Polimeni^3,4,5, Kawin Setsompop⁶, and William A Grissom^1,7

¹Vanderbilt University Institute of Imaging Science, Nashville, TN, United States, ²Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, United States, ³Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, ⁴Department of Radiology, Harvard Medical School, Boston, MA, United States, ⁵Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, United States, ⁶Radiological Sciences Laboratory, Stanford University, Standford, CA, United States, ⁷Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States

Synopsis

Achieving submillimeter-resolution BOLD fMRI is a challenge since single-shot EPI suffers from long echo times, blurring, and image distortions, while multishot EPI suffers from motion- and respiration-induced shot-to-shot phase errors. In shuttered multishot EPI, data are acquired in each shot after exciting a set of interleaved “shutters” across the imaged slice. This enables high quality reconstructions from each shot, which in turn enables navigator-free shot-wise phase and motion corrections prior to reconstructing a full-FOV image. Herein we describe a full motion- and phase-correcting image reconstruction for dynamic shuttered EPI and validate it in head motion and BOLD fMRI experiments.

This abstract and the presentation materials are available to members only; a login is required.

Join Here