Abstract #0376

Feasibility of magnetization transfer measurement in distinct white matter connections

Pietro Bontempi^1,2, Ilana R. Leppert³, Simona Schiavi^1,4, Jennifer S. W. Campbell³, Mark Nelson^3,5, Bruce G. Pike⁶, Christine L. Tardif^3,5,7, and Alessandro Daducci¹

¹Department of Computer Science, University of Verona, Verona, Italy, ²Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy, ³McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC, Canada, ⁴Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genova, Italy, ⁵Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada, ⁶Hotchkiss Brain Institute and Departments of Radiology and Clinical Neuroscience, University of Calgary, Calgary, AB, Canada, ⁷Department of Biomedical Engineering, McGill University, Montreal, QC, Canada

Synopsis

Magnetization Transfer (MT) imaging is a MR technique that sensitizes image contrast to protons bound to macromolecules such as protein and lipids. Using an innovative sequence that combines MT and diffusion- imaging, and Convex Optimization Modeling for Microstructure Informed Tractography (COMMIT), a method that allows estimation of bundle tissue properties, we investigate bundle specific MT ratio (MTR) values.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.