Sub-millimeter functional imaging at ultra high field (UHF) strengths can capture cortical layer-specific functional information flow within and across brain systems. However, UHF scanners are only available to appr. 100 privileged imaging centers, globally. In this work, we implement, characterise and apply a CBV-sensitive VASO sequence setup for widely accessible 3T scanners. We find that the longer T2*, and shorter T1 relaxation times at 3T can account for some of the lower z-magnetization in the inversion-recovery VASO sequence compared to 7T and 9.4T. We conclude that layer-fMRI VASO is applicable without too much further ado at 3T.
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