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Abstract #0428

Deformable Registration of Serial Micrographs to Post-Mortem MRI in the BigMac Dataset Using TIRL

Istvan N Huszar1, Adele Smart1, Saad Jbabdi1, Mark Jenkinson1, Amy FD Howard1, and Karla L Miller1
1Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom


The BigMac dataset combines extensive post-mortem MRI with histology and polarised light imaging (PLI) in a macaque brain. Adding a new extension to our recently developed platform, the Tensor Image Registration Library (TIRL), we address unique challenges associated with this dataset and successfully align 77 2-D polarised light micrographs to high-resolution structural MRI data.

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