In this study, we utilized MR elastography (MRE) and transversely isotropic inversion to estimate anisotropic material parameters of muscle during contraction states, including passive muscle lengthening and isometric contraction. We collected MRE and DTI data on six subjects and took averages of the parameters within the medial and lateral heads of the gastrocnemius muscle and compared the results during the contraction states. We found significant differences between the estimates during the various states of contraction. Here we demonstrate that MRE and TI-NLI can generate anisotropic parameter estimates for muscle tissue while capturing changes to functional aspects of the tissue.
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