We investigated the intravoxel incoherent imaging (IVIM) effect on neurite orientation dispersion and density imaging (NODDI) metric calculations in both healthy controls (N=36) and a clinical population of individuals with a psychotic spectrum disorder (PSD) (N=55) by extending the original model to include a microvascular blood compartment. We found that without controlling for the IVIM effect, several NODDI metrics were possibly misestimated, which subsequently affected group comparisons and results.
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