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Abstract #0495

4D free-breathing variable density stack-of-stars functional MR urography in young children without sedation: A clinical feasibility study

Jakob Spogis1, Christoph Katemann2, Shuo Zhang2, Ilias Tsiflikas1, Michael Esser1, and Jürgen Schäfer1
1Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany, 2Philips GmbH Market DACH, Hamburg, Germany


High-quality magnetic resonance urography (MRU) is clinically valuable to provide a comprehensive evaluation of the renal function and urinary tract in children without ionizing radiation. However, respiration-related patient motion remains a major challenge that impairs diagnostic image quality and hampers an accurate quantitative analysis. In this study, we adopt a novel high temporospatial resolution dynamic-contrast-enhanced (DCE) MRI technique based on 3D radial stack-of-stars gradient-echo sequence acquisition in combination with elliptical variable density k-space scheme for morphological and quantitative MRU and demonstrate its motion robustness in small children in free breathing without sedation.

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