Studying gray matter microstructure with dMRI is challenging because of partial volume effects and high orientation dispersion. In this work, we propose a novel method that combines spherical b-tensor encoding, strong diffusion weighting and super-resolution reconstruction to perform high-resolution microstructure imaging of gray matter. We map the tissue mean diffusivity and the microscopic anisotropy which, by their design, are unaffected by partial volume effects and intra-voxel orientation dispersion. We demonstrate the approach in human brain in vivo at a resolution of 1.4 mm isotropic.
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