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Abstract #0532

Quantitative Assessment of Whole Knee Joint Using a New Phase Modulated Ultrashort Echo Time Adiabatic T1rho (PM-UTE-AdiabT1rho) Sequence

Yajun Ma1, Michael Carl2, Alan Bao1, Hyungseok Jang 1, Saeed Jerban1, Alecio F Lombardi 1, Christine B Chung 1, Eric Y Chang1,3, and Jiang Du1
1Radiology, University of California, San Diego, San Diego, CA, United States, 2GE Healthcare, San Diego, CA, United States, 3Radiology Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, United States


Adiabatic T1rho (AdiabT1rho) is much less sensitive to the magic angle effect compared to the regular continuous wave T1rho (CW-T1rho). In this study we developed a novel phase modulated ultrashort echo time adiabatic T1rho (PM-UTE-AdiabT1rho) sequence for quantitative assessment of both short and long T2 tissue components in the knee joint, including cartilage, meniscus, ligaments, tendons, and muscle, on a clinical 3T scanner. Our results showed excellent single exponential fitting for all the major tissue components in both ex vivo and in vivo normal knee joints.

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