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Abstract #0533

Accelerating IVIM and DTI for assessing microstructural changes after acute hamstring injury

Susanne Rauh1, Jithsa Monte2, Melissa Hooijmans2, Joep Suskens3, Oliver Gurney-Champion2, Johannes Tol3, Mario Maas2, Aart Nederveen2, and Gustav Strijkers1
1Department of Biomedical Engineering and Physics, Amsterdam UMC, Amsterdam, Netherlands, 2Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands, 3Department of Orthopedic Surgery, Amsterdam UMC, Amsterdam, Netherlands


DTI and IVIM are sensitive to hamstring injuries, but suffer from long scan times. Using b-values above a certain threshold only (high-b DTI) or a simplified IVIM approach (sIVIM-DTI), which estimates the perfusion fraction and diffusion tensor, can reduce the scan time while inherently correcting DTI-indices for IVIM effects. We showed in this work that those methods provide similar sensitivity to hamstring injuries in comparison to a full IVIM-DTI fit while reducing acquisition time up to 42%. Since no difference in perfusion fraction was found between injury states, we suggest high-b DTI is the method of choice in this application.

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