Low back pain that have etiologies related to degenerative intervertebral(IVD) disc changes are difficult to diagnose and treat. Quantitative characterization of the lumbar spine IVD can potentially be useful in detecting early changes to the IVD. In this study a 3D-MR fingerprinting technique was employed that is capable of simultaneously quantifying four different parameters in a clinically feasible time. Five healthy subjects underwent lumbar spine 3D-MRF scans. The results demonstrate that 3D-MRF can simultaneously measure and generate T1, T2, T1ρ, and B1+ volumetric maps of lumbar spine in a single scan within clinically feasible scan time of about 10 minutes.
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