Can Ultrafast MRI replace conventional DCE MRI in morphological evaluation and subtype classification in breast mass lesions?
Akane Ohashi1, Masako Kataoka2, Mami Iima2, Maya Honda3, Rie Ota2, Yuta Urushibata 4, Dominic Marcel Nickel5, Masakazu Toi6, Sophia Zackrisson1, and Yuji Nakamoto2
1Translational Medicine, Diagnostic Radiology, Lund University, Skåne University Hospital, Malmö, Sweden, 2Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, 3Diagnostic Radiology, Kansai Electric Power Hospital, Osaka, Japan, 4Siemens Healthcare K.K., Tokyo, Japan, 5Siemens Healthcare GmbH, Erlangen, Germany, 6Breast Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
To evaluate the possibility of replacing conventional DCE MRI with UF-DCE MRI, we assessed the concordance of morphological information of the mass lesions between UF-DCE MRI and the early phase of DCE MRI. The size and shape showed excellent concordance between the two phases, while UF-DCE MRI tended to show circumscribed margin and homogeneous enhancement. In a sub-analysis, luminal subtypes demonstrated smaller size with homogeneous enhancement pattern compared with non-luminal subtypes. Predictive model for luminal subtype using the two parameters resulted in the AUC of 0.68, 0.72, for UF-DCE MRI and the early phase of DCE MRI, respectively (p=0.23).
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