Abstract #0581

Measurement of cardiac magnetostimulation thresholds in pigs

Valerie Klein^1,2, Jaume Coll-Font^2,3,4, Livia Vendramini², Donald Straney², Mathias Davids^1,2,3, Natalie G. Ferris^2,5, Lothar R. Schad¹, David E. Sosnovik^2,3,4,5, Christopher Nguyen^2,3,4, Lawrence L. Wald^2,3,5, and Bastien Guérin^2,3

¹Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Germany, Mannheim, Germany, ²Department of Radiology, Massachusetts General Hospital, A. A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, ³Harvard Medical School, Boston, MA, United States, ⁴Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Charlestown, MA, United States, ⁵Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, United States

Synopsis

We measured cardiac magnetostimulation thresholds in ten healthy pigs by discharging a 220-µF capacitor into a flat spiral coil placed close to the pigs’ torso. We used MR Dixon images to locate the porcine heart and determine the relative coil position to calculate the B-field in the heart (Biot-Savart). The average threshold for cardiac magnetostimulation during diastole was dB/dt≈1570±320 T/s at the center of the heart. This value is >10X greater than the IEC 60601-2-33 cardiac dB/dt limit for the effective stimulus duration of the magnetic stimulator system used in the experiments (0.45 ms).

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