Abstract #0592

Ultra-high field motion-corrected MRI can visualize the mesoscale organization of the human cerebellum.

Nikos Priovoulos¹, Mads Andersen^2,3, Vincent Oltman Boer⁴, and Wietske van der Zwaag¹

¹Spinoza Center for Neuroimaging, Amsterdam, Netherlands, ²Philips Healthcare, Copenhagen, Denmark, ³Lund University Bioimaging Center, Lund University, Lund, Sweden, ⁴Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Amager and Hvidovre, Copenhagen, Denmark

Synopsis

The cerebellum is an important but challenging to image part of the human brain, due to its thin and highly-folded cortex. Here we demonstrate that using motion-corrected high-resolution 7T-MRI data, we can derive segmentations and surfaces of the cerebellar cortex with unprecedented accuracy in vivo. We expect this technique to greatly facilitate cognitive and clinical neuroscience research in the cerebellum.

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