Ultra-high field motion-corrected MRI can visualize the mesoscale organization of the human cerebellum.
Nikos Priovoulos1, Mads Andersen2,3, Vincent Oltman Boer4, and Wietske van der Zwaag1
1Spinoza Center for Neuroimaging, Amsterdam, Netherlands, 2Philips Healthcare, Copenhagen, Denmark, 3Lund University Bioimaging Center, Lund University, Lund, Sweden, 4Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Amager and Hvidovre, Copenhagen, Denmark
The cerebellum is an important but challenging to image part of the human brain, due to its thin and highly-folded cortex. Here we demonstrate that using motion-corrected high-resolution 7T-MRI data, we can derive segmentations and surfaces of the cerebellar cortex with unprecedented accuracy in vivo. We expect this technique to greatly facilitate cognitive and clinical neuroscience research in the cerebellum.
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