An automated AI-based method for liver image prescription from a localizer was recently proposed. In this work, this AI method was further evaluated in a larger retrospective patient cohort (1,039 patients for training/testing), across pathologies, field strengths, and against radiologists’ inter-reader reproducibility performance. AI-based 3D axial prescription achieved a S/I shift of <2.3 cm compared to manual prescription for 99.5% of test dataset. The AI method performed well across all sub-cohorts and better in 3D axial prescription than radiologists’ inter-reader reproducibility performance. The AI method was successfully implemented on a clinical MR system and showed robust performance across localizer sequences.
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