Abstract #0600

Dependence of liver R2* on the fat spectral model.

Gavin Hamilton¹, Alexandra N Schlein¹, Walter C Henderson¹, Danielle N Batakis¹, Lael K Ceriani¹, Ashley L Louie¹, Michael S Middleton¹, Yesenia Covarrubias¹, Kathryn J Fowler¹, and Claude B Sirlin¹

¹Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, United States

Synopsis

Using MRS, we examined whether the assumed fat spectral model (6-, or 9-peak) altered liver R2* estimation in vivo. We found that liver R2* estimation was model-independent, and liver R2*was not significantly different from water R2* (p = 0.07). However, fat R2* values estimated for these models were different (p < 0.0001), suggesting that fat R2* estimation in high-fat tissues may be model dependent.

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