Dependence of liver R2* on the fat spectral model.
Gavin Hamilton1, Alexandra N Schlein1, Walter C Henderson1, Danielle N Batakis1, Lael K Ceriani1, Ashley L Louie1, Michael S Middleton1, Yesenia Covarrubias1, Kathryn J Fowler1, and Claude B Sirlin1
1Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, United States
Using MRS, we examined whether the assumed fat spectral model (6-, or 9-peak) altered liver R2* estimation in vivo. We found that liver R2* estimation was model-independent, and liver R2*was not significantly different from water R2* (p = 0.07). However, fat R2* values estimated for these models were different (p < 0.0001), suggesting that fat R2* estimation in high-fat tissues may be model dependent.
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