Neonatal hypoxic ischemic encephalopathy (HIE) is a serious neurological condition, representing a primary cause of neonatal death and developmental impairment. In newborns with HIE, hyperperfusion is related to severe adverse outcomes, but less is known about the link between perfusion and mild to moderate developmental impairments. Using a voxelwise correlation analysis, we investigated the link between ASL perfusion in newborns with HIE and developmental outcome at 2 years. A more adverse outcome was associated with hyperperfusion across the whole brain. A better cognitive outcome was associated with lower perfusion in the bilateral basal ganglia, thalamus, hippocampus and cerebellum.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords