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Abstract #0617

Predictive Bladder Urodynamics Using Real-Time Magnetic Resonance Imaging: A Pilot Study

Labib Shahid1, Juan Pablo Gonzalez-Pereira1, Cody Johnson1, Yanheng Li2, David Rowinski2, and Alejandro Roldán-Alzate1
1University of Wisconsin-Madison, Madison, WI, United States, 2Convergent Science, Inc., Madison, WI, United States

Synopsis

Multi-channel urodynamics is an invasive diagnostic method used to assess bladder biomechanics. MRI-based CFD has shown high potential as a clinical tool primarily focused on cardiovascular flows. In this pilot study, we demonstrate MRI-based CFD as a tool to study urodynamics. Real-time MRI on one subject provided bladder wall surfaces at multiple time points during voiding. We developed a surface mapping algorithm that processes the bladder geometries before inputting them into a CFD simulation. Coupling MRI with CFD successfully visualized and quantified urine flow dynamics. This provides a non-invasive tool to investigate urodynamics in common urological conditions such as BPH/LUTS.

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Keywords