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Abstract #0668

Muscle hypertrophy in resistance training assessed with Diffusion Tensor Imaging

Valentina Mazzoli1, Elka Rubin 1, Marco Barbieri1, Andrew Schmidt1, Lauren Watkins1, Akshay Chaudhary1, Feliks Kogan1, and Garry Gold1
1Department of Radiology, Stanford University, Stanford, CA, United States


5 healthy subjects consistently performed a declined squad training routine for 3 months. Every subject received an MRI scan before undergoing the training and subsequently every month until the end of the training. We observed a decrease in AD, MD and FA over the course of training, with a significant change after 1 month. Muscle volume increased, with changes only apparent at 3 months. Changes in diffusion parameters were predictive of changes in global volume. Our study shows that DTI can be a sensitive tool to study muscle hypertrophy and could be used for early monitoring of training and rehabilitation.

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