COVID-19 is known to result in neurological manifestations which sometimes correlate with neuroimaging abnormalities. Understanding these abnormalities requires further systematic study. We undertook a retrospective analysis of 60 MRIs from hospitalized COVID-19 patients (20 intubated, 20 non-brain cancer, and 20 non-intubated/non-cancer) with neurological manifestations. Neuroimaging showed non-infarct parenchymal T2/FLAIR signal hyperintensities (26.7%), acute/subacute infarcts (25%), microhemorrhages (21.7%), chronic infarcts (18.3%), chronic macrohemorrhages (10%), and acute macrohemorrhages (6.7%). Common neurological symptoms were confusion/encephalopathy/delirium (70%), generalized weakness (38.3%), and impaired responsiveness/coma (38.3%). Thus, COVID-19 may be associated with neuroimaging abnormalities. Differences in abnormalities were seen based on permutations of cancer and intubation.
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