Abstract #0737

Optimisation of Structural MR Imaging Sequences in a Neonatal Cohort at 64 mT

Paul Cawley^1,2, Francesco Padormo^1,3, UNITY Consortium⁴, Louise Dillon¹, Emer Hughes¹, Jennifer Almalbis¹, Joanna Robinson^1,2, Alessandra Maggioni^1,2, Daniel Cromb^1,2, Lori Arlinghaus⁵, Houchun Harry Hu⁵, Steve Williams⁴, Serena Counsell¹, Tomoki Arichi¹, Mary Rutherford¹, Joseph V. Hajnal¹, and A. David Edwards^1,2

¹Centre for the Developing Brain, King's College London, London, United Kingdom, ²Neonatal Intensive Care Unit, Guy's & St Thomas' Hospital NHS Foundation Trust, London, United Kingdom, ³Medical Physics, Guy's & St Thomas' Hospital NHS Foundation Trust, London, United Kingdom, ⁴Centre for Neuroimaging Sciences, King's College London, London, United Kingdom, ⁵Hyperfine, Inc., Guildford, CT, United States

Synopsis

Point-of-care Magnetic Resonance scanning is a novel and potentially transformative technology, utilising Ultra-Low Field permanent magnets to facilitate bedside neuroimaging. Through iterative T2w sequence optimisation, we demonstrate the feasibility of using ultra-low field portable 64mT MR scanning in neonates. This pilot data demonstrates that images can provide sufficient contrast for tissue differentiation and identify pathological lesions. Scanning with ongoing intensive care was both feasible and safe.

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