Optimisation of Structural MR Imaging Sequences in a Neonatal Cohort at 64 mT
Paul Cawley1,2, Francesco Padormo1,3, UNITY Consortium4, Louise Dillon1, Emer Hughes1, Jennifer Almalbis1, Joanna Robinson1,2, Alessandra Maggioni1,2, Daniel Cromb1,2, Lori Arlinghaus5, Houchun Harry Hu5, Steve Williams4, Serena Counsell1, Tomoki Arichi1, Mary Rutherford1, Joseph V. Hajnal1, and A. David Edwards1,2
1Centre for the Developing Brain, King's College London, London, United Kingdom, 2Neonatal Intensive Care Unit, Guy's & St Thomas' Hospital NHS Foundation Trust, London, United Kingdom, 3Medical Physics, Guy's & St Thomas' Hospital NHS Foundation Trust, London, United Kingdom, 4Centre for Neuroimaging Sciences, King's College London, London, United Kingdom, 5Hyperfine, Inc., Guildford, CT, United States
Point-of-care Magnetic Resonance scanning is a novel and potentially transformative technology, utilising Ultra-Low Field permanent magnets to facilitate bedside neuroimaging. Through iterative T2w sequence optimisation, we demonstrate the feasibility of using ultra-low field portable 64mT MR scanning in neonates. This pilot data demonstrates that images can provide sufficient contrast for tissue differentiation and identify pathological lesions. Scanning with ongoing intensive care was both feasible and safe.
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